Prenatal detection of thalassemia by cell-free fetal DNA (cffDNA) in maternal plasma using surface enhanced Raman spectroscopy combined with PCR
نویسندگان
چکیده
منابع مشابه
Detection and quantification by homogeneous PCR of cell-free fetal DNA in maternal plasma.
Prenatal diagnosis of genetic disorders has traditionally relied on invasive procedures such as amniocentesis and chorionic villus sampling (CVS). As these procedures carry a small but significant risk of pregnancy loss, a convenient noninvasive prenatal diagnostic has long been sought. Although fetal cells circulating in the maternal blood have been used for prenatal screening, because of thei...
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ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2018
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.9.003167